The official website of the University of Tokyo in Japan recently announced that researchers at the University of Tokyo and Kyoto University have discovered the molecular mechanism of RNA interference (RNAi). The so-called ribonucleic acid interference is a phenomenon in which certain protein synthesis occurs when single-molecule RNA is split.
Since RNAi can shut down the expression of specific genes, scientists have been expecting RNAi to be used in the medical field. In previous studies, scientists have discovered that RNAi is regulated by the RNA-induced silencing complex (RISC), and that the center of the RISC contains a small RNA and an alpha protein that can cleave the target RNA. However, the scientific community has not found a tool to directly monitor RNAi responses, so the molecular mechanism of RNAi has also been a mystery.
For the first time, Japanese researchers have designed a single-molecule imaging analysis method that can observe the process of RISC splitting target RNA in real time in a test tube. They observed that the small RNA in RISC contains two parts, some of which are quickly "bound" to the target RNA to be split, and the other part is responsible for "calibration" whether the correct target RNA is selected.
This breakthrough result reveals the mechanism of action of RISC, or will accelerate the scientific research on RNAi, such as the development of RNA-based gene therapy drugs that inhibit the growth of certain pathogenic proteins.
General Purpose Powder-Actuated System is used for building fastening, which have three parts: Actuated tools, Cartridges and fasteners. When Actuated Tool strikes cartridge and cartridge will explode in the inner of tools and produce a lot of high temperature and high pressure gas. The gas will push the piston and the piston will push the fasteners into the basement. Or the gas will push the fasteners directly into the basement. Like this, we can fix a lot of things into concrete and steel basement tightly.
The fundamental is as the following:
The Actuated tools are classified for direct tools and undirect tools, we can also called high velocity and Low velocity tool, the fundamental is as the following:
High velocity tool:
Low velocity tool:
Based on different purpose, Cartridges are classified for different calibers and dimensions. The usual caliber and dimension is as the following:
.27calX11mm(S1)
.22calx15mm(S5)
.22calx16mm(S52)
.27calx18mm(S3)
.25calX16mm(S43)
At the same time, each caliber cartridge is classified for different specification based on the quantity of inner powder, which is marked by different color. when the color is more darker, the power level is stronger. otherwise, the power lever is lighter.
The fasteners are classified for different categories. Each different category is classified for different specification based on different length and diameter. At the same time, it is can also be re-designed based on special use.
The packages are as the following:
1. Tools: one tool/ plastic box/carton or five boxes/carton
2.Cartridge: 100pcs/paper or plastic box, 100boxes/carton.
3. Fasteners: 100pcs/paper box, XX boxes/carton.
For shipment, all cartons will packed by pallet.
General Purpose Powder-Actuated Systems
General Purpose Powder-Actuated Systems,Powder-Actuated Systems,Powder Actuated Fasteners,Powder Actuated Fastening System
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